Ex vivo permeation study jams

Studies and methodologies on vaginal drug permeation ...

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9/15/2015 · Studies and methodologies on vaginal drug permeation ... it is of great importance to implement accurate and reproducible methods to predict drug permeation. The in vitro and ex vivo tests should be privileged, ... Y.W. ChienIn vitro permeation study of a mucoadhesive drug delivery system for controlled delivery of nonoxynol-9.

Studies and methodologies on vaginal drug permeation ...

Discover the world's research - researchgate.net

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Discover the world's research - researchgate.net

Discover the world's research - researchgate.net

Time Dependent Rheological Characteristics of Pineapple Jam

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Time Dependent Rheological Characteristics of Pineapple Jam. ... Ex vivo permeation studies witnessed high permeation and deposition of resveratrol in skin when compared to plain resveratrol ...

Time Dependent Rheological Characteristics of Pineapple Jam

Study of penetration mechanism of labrasol on rabbit ...

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6/15/2018 · Much more systematic research, for instance, a range of compounds including both hydrophilic and lipophilic would be applied synchronously as model drugs to investigate the corneal penetration enhancing effects of labrasol, and also the further in vivo study would be required to explore insights into the complex mechanisms.

Study of penetration mechanism of labrasol on rabbit ...

Intestinal Barrier Function: Molecular Regulation and ...

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Introduction. The intestinal epithelium is a single layer of cells lining the gut lumen and has two critical functions. Firstly, it acts as a barrier to prevent the passage of harmful intraluminal entities including foreign antigens, microorganisms and their toxins 1, 2.Its second function is to act as a selective filter allowing the translocation of essential dietary nutrients, electrolytes ...

Intestinal Barrier Function: Molecular Regulation and ...

The kidney tight junction (Review) - PubMed Central (PMC)

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10/1/2014 · The tight junction is an important subcellular organelle which plays a vital role in epithelial barrier function. Claudin, as the integral membrane component of tight junctions, creates a paracellular transport pathway for various ions to be reabsorbed by the kidneys. This review summarizes advances ...

The kidney tight junction (Review) - PubMed Central (PMC)

ILDR1 is important for paracellular water transport and ...

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5/16/2017 · The role of tight junction in water homeostasis is an important but understudied area. Here, we reveal a paracellular water permeation pathway made by the tricellular tight junction and regulated by its integral protein, known as Ildr1. The importance of paracellular water permeation is demonstrated here with emphasis of its potential role in causing urinary concentrating defects in the kidney.

ILDR1 is important for paracellular water transport and ...

Temporal and regional intestinal changes in permeability ...

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We find that changes in in vivo and ex vivo permeability are time and region dependent, and that expression of tight junction and inflammatory genes are modulated in both temporal and regional specificity. Using modeling approaches, we also provide models of changes in these genes following estrogen deficiency.

Temporal and regional intestinal changes in permeability ...

US20080004218A1 - Methods for enhanced epithelial ...

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US20080004218A1 - Methods for enhanced epithelial permeation of y2 receptor-binding peptides for treating and preventing obesity - Google Patents Methods for enhanced epithelial permeation of y2 receptor-binding peptides for treating and preventing obesity ... (JAMs), occludins, or claudins. Examples of this are antibodies, antibody fragments ...

US20080004218A1 - Methods for enhanced epithelial ...

Endothelial permeability, LDL deposition, and ...

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Vascular wall permeability to LDL can now also be measured using in vivo/ex vivo methods. In vivo/ex vivo measurements of LDL uptake in carotid and aorta can be assessed by administering radiolabelled LDL, followed by autoradiography. 28, 29 This method consists in obtaining LDL from animal or human plasma in vivo, labelling the lipoprotein ...

Endothelial permeability, LDL deposition, and ...

Models and Methods to Evaluate Transport of Drug Delivery ...

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These models also allow tissue explants to be cultured for ex vivo studies, prior to validation in vivo 17,18. In conclusion, the methods used in this study have provided valuable preliminary information regarding the transport of a model drug delivery system, in terms of efficiency, across cell monolayers.

Models and Methods to Evaluate Transport of Drug Delivery ...

menthone, 89-80-5 - The Good Scents Company

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A family company dedicated to sales and distribution: Flexibility, availability, price and quality. Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.

menthone, 89-80-5 - The Good Scents Company

US7863245B2 - Compositions for enhanced epithelial ...

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US7863245B2 - Compositions for enhanced epithelial ...

US7863245B2 - Compositions for enhanced epithelial ...

Prepared by R.R. Donnelley Financial -- EX-10.4

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EX-10.4 2 d721131dex104.htm EX-10.4 Exhibit 10.4 . INTELLECTUAL PROPERTY LICENSE AGREEMENT ... the therapeutic or prophylactic agent itself or chemical permeation enhancers, or (ii) the use of a Microprojection System for sampling or sensing. ... days following the submission by TMC to the FDA of a protocol for the Phase II study of the PTH ...

Prepared by R.R. Donnelley Financial -- EX-10.4

Propylparaben | C10H12O3 - PubChem

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Propylparaben is the benzoate ester that is the propyl ester of 4-hydroxybenzoic acid.Preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos and bath products.Also used as a food additive. It has a role as an antifungal agent and an antimicrobial agent.

Propylparaben | C10H12O3 - PubChem

BPS Publications - bpspubs.onlinelibrary.wiley.com

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A study performed in immunocompetent Balb/c mice fed with GSPs showed tumour‐growth inhibition with an increase in the survival period and inhibition of metastatic status (Gollucke et al., 2013). Similar results were observed in other in vivo cancer models (Gollucke et al., 2013). Moreover, it has been demonstrated that GSPs inhibit the ...

BPS Publications - bpspubs.onlinelibrary.wiley.com

Gold Nanoparticles Increase Endothelial Paracellular ...

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8/13/2015 · Based on the results of both in vitro and in vivo assays, we conclude that Au-NP-induced Evans dye diffusion in brain might result from endothelial TJ damage and BBB leakiness. In this study, we first determined that Au-NPs increased endothelial paracellular permeability in vitro and enhanced BBB permeability in vivo. Our results also provided ...

Gold Nanoparticles Increase Endothelial Paracellular ...

JoVE | Peer Reviewed Scientific Video Journal - Methods ...

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The in vitro study showed minimum hemolysis in the optimized formulation. Finally, in vivo toxicity studies followed with hisptopathological assessment showed that elastic liposome was able to extract SC to improve drug permeation without changing general anatomy of the skin.

JoVE | Peer Reviewed Scientific Video Journal - Methods ...

Lecture: New light on the role of claudins in the kidney

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Lecture: New light on the role of claudins in the kidney Jianghui Hou ... Lecture New light on the role of claudins in the kidney Jianghui Hou Renal Division; Washington University; St. Louis, MO USA Keywords: tight junction, calcium, ... were isolated and perfused ex vivo, the ...

Lecture: New light on the role of claudins in the kidney

Glycomacropeptide: Biological Activities and Uses | IntechOpen

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Glycomacropeptide (GMP) is a milk-derived bioactive peptide that comprises 15–20% of proteins present in whey, being the third most abundant. It is released from κ-casein by enzymatic digestion, either physiologically or in industry during cheese making process. GMP has many biological activities that are of particular interest for the manufacture of novel functional foods.

Glycomacropeptide: Biological Activities and Uses | IntechOpen

Restoration of Barrier Function in Injured Intestinal ...

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However, utilizing an ex vivo porcine model of acute intestinal injury, we have shown that recovery of barrier function (in terms of TER) coincides with the assembly of TJ proteins such as ZO-1 and occludin to the TJs, confirming findings observed in epithelial cell culture systems . We have accumulated convincing evidence for a role of ...

Restoration of Barrier Function in Injured Intestinal ...
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